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Recommended Reading

Mogenson GJ, Jones DL, Yim CY. From motivation to action: functional interface between the limbic system and the motor system. Prog Neurobiol. 1980;14:69-97. PMID: 6999537
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Kalivas PW, Barnes CD (Ed). Limbic motor circuits and neuropsychiatry, CRC Press, 1993.

Berridge KC. Food reward: brain substrates of wanting and liking. Neurosci Biobehav Rev. 1996;20:1-25. PMID: 8622814
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Spanagel R and Zieglgansberger W. Anti-craving compounds for ethanol: new pharmacological tools to study addictive processes. Trends in Pharmacological Sciences 1997;18:54-59. PMID:  9090311
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Jog MS, Kubota Y, Connolly CI, Hillegaart V, Graybiel AM. Building neural representations of habits. Science. 1999;286:1745-1749. PMID: 10576743
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Tremblay, L., and W. Schultz. "Relative reward preference in primate orbitofrontalcortex." Nature 1999;398:704-708. PMID: 10227292
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Nestler EJ. Neurobiology. Total recall-the memory of addiction. Science. 2001;292:2266-2267. PMID: 11423644
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Graybiel AM. Neural networks: neural systems V: basal ganglia. Am J Psychiatry. 2001 ;158:21. PMID: 11136627
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Holden C. 'Behavioral' addictions: do they exist? Science. 2001;294:980-982. PMID: 11691967
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O'Doherty J, Kringelbach ML, Rolls ET, Hornak J, Andrews C. Abstract reward and punishment representations in the human orbital frontal cortex. Nature Neuroscience 2001;4:95-102.
Nature Neuroscience

Spiro JE. Reward and punishment in orbital frontal cortex. Nature Neuroscience 2001;4:12.
Nature Neuroscience

Dayan P, Balleine BW. Reward, motivation, and reinforcement learning. Neuron. 2002;36:285-298. PMID:  12383782
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McFarland K, Lapish CC, Kalivas PW. Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior.J Neurosci. 2003;23:3531-3537. PMID:  12716962
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Delgado MR, Locke HM, Stenger VA, Fiez JA. Dorsal striatum responses to reward and punishment: effects of valence and magnitude manipulations. Cogn Affect Behav Neurosci. 2003;3:27-38. PMID: 12822596
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Shizgal P and Arvanitogiannis A. Gambling on dopamine. Science 2003;299:1856-1858. PMID:  12649473
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Gottfried JA, O'Doherty J, Dolan RJ. Encoding predictive reward value in human amygdale and orbital frontal cortex. Science 2003;301:1104-1107.

Schoenbaum G, Setlow B, Saddoris M, Gallagher M. Encoding predicted outcome and acquired value in orbital frontal cortex during cue sampling depends upon input from basolateral amygdale. Neuron 2003;39:855-867.

Fiorillo CD, Tobler PN, Schultz W. Discrete coding of reward probability and uncertainty by dopamine neurons. Science 2003;299:1898-1902.
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Nestler EJ. Molecular mechanisms of drug addiction. Neuropharmacology. 2004;47 Suppl 1:24-32. PMID: 15464123
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Nestler EJ and Malenka RC: The addicted brain. Scientific American 2004;78-85. PMID:  14981881
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O'Doherty J, Dayan P, Schultz J, Deichmann R, Friston K, Dolan RJ. Dissociable roles of ventral and dorsal striatum in instrumental conditioning. Science. 2004;304:452-454. PMID: 15087550
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O'Doherty, J., P. Dayan,J. Schultz, R. Deichmann, K. Friston, and R. Dolan. "Dissociable Roles of Ventral and Dorsal Striatum in Instrumental Conditioning."Science 2004;304:452-454. PMID: 15087550
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Roesch MR and Olson CR. Neuronal activity related to reward value and motivation in primate frontal cortex. Science 2004;304:307-310.
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Chuhma N, Zhang H, Masson J, Zhuang H, Sulzer D, Hen R, Rayport S. Dopamine neurons mediate a fast excitatory signal via their glutamatergic synapses. J Neurosciences 2004;24:972-981. PMID:  14749442
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Kalivas PW, Volkow ND. The neural basis of addiction: a pathology of motivation and choice. Am J Psychiatry. 2005;162:1403-1413.
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http://hhmi.org/news/wang_yu20051125.html

Everitt BJ, Robbins TW. Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nat Neurosci. 2005;8:1481-1489.
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Hsu, M,. M. Bhat, R. Adolphs, D. Tranel, and C. F. Camerer. "Neural SystemsResponding to Degrees of Uncertainty in Human Decision - Making" Science 2005;310:1680-1683. PMID:  16339445
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Hyman SE. Addiction: a disease of learning and memory. Am J Psychiatry. 2005;162:1414-1422. PMID: 16055762
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Am J Psychiatry

Hok V, Save E, Lenck-Santini PP, Poucet B. Coding for spatial goals in the prelimbic/infralimbic area of the rat frontal cortex. Proc Natl Acad Sci U S A. 2005;102:4602-4607. PMID: 15761059
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Goto Y and Grace AA. Dopaminergic modulation of limbic and cortical drive of nucleus accumbens in goal-directed behavior. Nature Neuroscience 2005;8:805-812. PMID:  15908948
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Graybiel AM. Basal ganglia: learning new tricks and loving it. Current Opinion in Neurobiology 2005;15:638-644. PMID:  16271465
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Hyman SE, Malenka RC, Nestler E. Neural Mechanisms of Addiction: The Role of Reward-Related Learning and Memory. Annu Rev Neurosci. 2006 Apr 20.
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Yin HH, Knowlton BJ. The role of the basal ganglia in habit formation. Nat Rev Neurosci. 2006;7:464-476. PMID:  16715055
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Pierce RC and Kumaresan V. The mesolimbic dopamine system: the final common pathway for the reinforcing effect of drugs of abuse. Neuroscience and Behavioral Review 2006;30:215-238. PMID:  16099045
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Grabbing Addiction by the Tail by y.T. Wang, November 25, 2005, Howard Hughes Medical Institute.
Howard Hughes Medical Institute

Encoding predictive reward value in human amygdale and orbital frontal
cortex., Science 2003:301:1104-1107.
Science

Redish (2004) "Addiction as a computational process gone awry" Science
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Science

Schoenbaum G, Setlow B, Saddoris M, Gallagher M. Encloding predicted
outcome and acquired value in orbital frontal cortex during cue sampling
depends upon input from basolateral amygdale. Neuron 2003;39:855-867.
Science Direct

Yoshida W and Ishii S. Resolution of Uncertainty in Prefrontal Cortex
Neuron, Volume 50, Issue 5, 1 June 2006, Pages 781-789

Haber SN, Fudge JL and McFarland NR. Striatonigrostriatal pathways in primates form an ascending spiral from the shell to the dorsolateral striatum. J Neurosci. 2000 Mar 15;20(6):2369-82. PMID: 10704511
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Fellows LK, Farah MJ. Ventromedial frontal cortex mediates affective shifting in humans: evidence from a reversal learning paradigm. Brain. 2003;126:1830-1837. PMID: 12821528
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Oxford Journals
 

Fellows LK, Farah MJ. Different underlying impairments in decision-making following ventromedial and dorsolateral frontal lobe damage in humans.
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Zald DH. The rodent orbitofrontal cortex gets time and direction.Neuron. 2006 Aug 17;51(4):395-7. PMID: 16908405
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Rescorla RA. Pavlovian conditioning. It's not what you think it is. Am Psychol. 1988 Mar;43(3):151-60. PMID: 3364852
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Tindell AJ, Smith KS, Pecina S,Berridge KC and Aldridge JW. Ventral pallidum firing codes hedonic reward: when a bad taste turns good. J Neurophysiol. 2006 Aug 2; PMID: 16885520
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Zald, D.H. & Rauch, S.L. (Eds). The Orbital Frontal Cortex.  Oxford University Press, Oxford U.K. 2006

Nasir H. Naqvi, David Rudrauf, Hanna Damasio, and Antoine Bechara. Damage to the Insula Disrupts Addiction to Cigarette Smoking. Science 2007;315: 531-534.

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